The C. elegans Opa1 homologue EAT-3 is essential for resistance to free radicals.

The C. elegans Opa1 homologue EAT-3 is essential for resistance to free radicals.

The C. elegans eat-3 gene encodes a mitochondrial dynamin family member homologous to Opa1 in humans and Mgm1 in yeast. We find that mutations in the C. elegans eat-3 locus cause mitochondria to fragment in agreement with the mutant phenotypes observed in yeast and mammalian cells. Electron microsco...

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Bibliographic Details
Main Authors: Takayuki Kanazawa, Mauro D Zappaterra, Ayako Hasegawa, Ashley P Wright, Erin D Newman-Smith, Karolyn F Buttle, Kent McDonald, Carmen A Mannella, Alexander M van der Bliek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2265488?pdf=render

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http://europepmc.org/articles/PMC2265488?pdf=render

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