Association of miR-146a, miR-149, miR-196a2, and miR-499 Polymorphisms with Ossification of the Posterior Longitudinal Ligament of the Cervical Spine.

Ossification of the posterior longitudinal ligament (OPLL) of the spine is considered a multifactorial and polygenic disease. We aimed to investigate the association between four single nucleotide polymorphisms (SNPs) of pre-miRNAs [miR-146aC>G (rs2910164), miR-149T>C (rs2292832), miR-196a2T&g...

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Main Authors: Jae Joon Lim, Dong Ah Shin, Young Joo Jeon, Hemant Kumar, Seil Sohn, Hyoung Sik Min, Jang Bo Lee, Sung Uk Kuh, Keung Nyun Kim, Jung Oh Kim, Ok Joon Kim, Alexander E Ropper, Nam Keun Kim, In Bo Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4959720?pdf=render