Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans.

Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans.

Neurodegeneration has been correlated with mitochondrial DNA (mtDNA) damage and exposure to environmental toxins, but causation is unclear. We investigated the ability of several known environmental genotoxins and neurotoxins to cause mtDNA damage, mtDNA depletion, and neurodegeneration in Caenorhab...

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Bibliographic Details
Main Authors: Claudia P González-Hunt, Maxwell C K Leung, Rakesh K Bodhicharla, Madeline G McKeever, Andrew E Arrant, Kathleen M Margillo, Ian T Ryde, Derek D Cyr, Sara G Kosmaczewski, Marc Hammarlund, Joel N Meyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4259338?pdf=render

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http://europepmc.org/articles/PMC4259338?pdf=render

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