Effects of biomarker diagnostic accuracy on biomarker-guided phase 2 trials

Recent advancements in genomics have attracted attention towards biomarker-guided trials. These trials aim to identify therapies that target diseases based on their genetic profile, and are especially common in cancer research. Careful incorporation of biomarkers in phase II studies is critical to t...

Full description

Bibliographic Details
Main Authors: Jay JH. Park, Ofir Harari, Louis Dron, Edward J. Mills, Kristian Thorlund
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Contemporary Clinical Trials Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865419300912