Periodontal pathogens alter the synovial proteome. Periodontal pathogens do not exacerbate macroscopic arthritis but alter the synovial proteome in mice.

Rheumatoid arthritis (RA) and periodontitis (PD) are chronic inflammatory diseases that appear to occur in tandem. However, the mutual impact PD exerts on RA and vice versa has not yet been defined. To address this issue, we set up an animal model and analyzed how two prime inducers of periodontitis...

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Bibliographic Details
Main Authors: Anna-Lena Buschhart, Lennart Bolten, Johann Volzke, Katharina Ekat, Susanne Kneitz, Stefan Mikkat, Bernd Kreikemeyer, Brigitte Müller-Hilke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242868