A high level of lncFGD5-AS1 inhibits epithelial-to-Mesenchymal transition by regulating the miR-196a-5p/SMAD6/BMP axis in gastric Cancer

A high level of lncFGD5-AS1 inhibits epithelial-to-Mesenchymal transition by regulating the miR-196a-5p/SMAD6/BMP axis in gastric Cancer

Abstract Background Long non-coding RNA (lncRNA) was a vital factor in the progression and initiation of human cancers. This study found a new lncRNA, FGD5-AS1, which can inhibit EMT process, proliferation, and metastasis in vitro and in vivo. Methods qRT-PCR was employed to test the expression of l...

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Bibliographic Details
Main Authors: Lin Liu, Cheng Zhang, Jizhao Wang, Xu Liu, Hangying Qu, Guangjian Zhang, Ting Liang, Jiansheng Wang, Jia Zhang
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Cancer
Subjects:
lncFGD5-AS11
miR-196a-5p2
ceRNA3
Epithelial-mesenchymal transition4
Prognose of gastric Cancer
Online Access:https://doi.org/10.1186/s12885-021-08192-x

Internet

https://doi.org/10.1186/s12885-021-08192-x

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