In Situ Detection of Adeno-associated Viral Vector Genomes with SABER-FISH

In Situ Detection of Adeno-associated Viral Vector Genomes with SABER-FISH

Gene therapy with recombinant adeno-associated viral (AAV) vectors is a promising modality for the treatment of a variety of human diseases. Nonetheless, there remain significant gaps in our understanding of AAV vector biology, due in part to the lack of robust methods to track AAV capsids and genom...

Full description

Bibliographic Details
Main Authors: Sean K. Wang, Sylvain W. Lapan, Christin M. Hong, Tyler B. Krause, Constance L. Cepko
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
in situ hybridization
AAV
gene therapy
viral vectors
microglia
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050120302072

Internet

http://www.sciencedirect.com/science/article/pii/S2329050120302072

Similar Items