Aggregate formation prevents dTDP-43 neurotoxicity in the Drosophila melanogaster eye

Aggregate formation prevents dTDP-43 neurotoxicity in the Drosophila melanogaster eye

TDP-43 inclusions are an important histopathological feature in various neurodegenerative disorders, including Amyotrophic Lateral Sclerosis and Fronto-Temporal Lobar Degeneration. However, the relation of these inclusions with the pathogenesis of the disease is still unclear. In fact, the inclusion...

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Bibliographic Details
Main Authors: Lucia Cragnaz, Raffaela Klima, Natasa Skoko, Mauricio Budini, Fabian Feiguin, Francisco E. Baralle
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Neurobiology of Disease
Subjects:
TDP-43
TBPH
ALS
Drosophila melanogaster
Aggregate
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114002034

Internet

http://www.sciencedirect.com/science/article/pii/S0969996114002034

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