Enhanced Healing of Diabetic Wounds by Topical Administration of Adipose Tissue-Derived Stromal Cells Overexpressing Stromal-Derived Factor-1: Biodistribution and Engraftment Analysis by Bioluminescent Imaging

Chronic ulcers represent a major health problem in diabetic patients resulting in pain and discomfort. Conventional therapy does not guarantee adequate wound repair. In diabetes, impaired healing is partly due to poor endothelial progenitor cells mobilisation and homing, with altered levels of the c...

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Bibliographic Details
Main Authors: Giuliana Di Rocco, Antonietta Gentile, Annalisa Antonini, Francesca Ceradini, Joseph C. Wu, Maurizio C. Capogrossi, Gabriele Toietta
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.4061/2011/304562