Paroxysmal nocturnal hemoglobinuria: pathophysiology, natural history and treatment options in the era of biological agents

Antonio M Risitano, Bruno RotoliHematology, Department of Biochemistry and Medical Biotechnologies, Federico II University of Naples, ItalyAbstract: Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal non-malignant hematological disease characterized by the expansion of hematopoietic stem cells (H...

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Bibliographic Details
Main Authors: Antonio M Risitano, Bruno Rotoli
Format: Article
Language:English
Published: Dove Medical Press 2008-06-01
Series:Biologics : Targets & Therapy
Online Access:http://www.dovepress.com/paroxysmal-nocturnal-hemoglobinuria-pathophysiology-natural-history-an-a1727