Hydrogen peroxide induces a specific DNA base change profile in the presence of the iron chelator 2,2’ dipyridyl in Escherichia coli

Hydrogen peroxide induces a specific DNA base change profile in the presence of the iron chelator 2,2’ dipyridyl in Escherichia coli

Pretreatment of Escherichia coli cultures with the iron chelator 2,2&#8217;-dipyridyl (1 mM) protects against the lethal effects of low concentrations of hydrogen peroxide (<15 mM). However, at H2O2 concentrations equal to or greater than 15 mM, dipyridyl pretreatment increases lethality and...

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Bibliographic Details
Main Authors: D.L. Felício, C.E.B. Almeida, A.B. Silva, A.C. Leitão
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2009-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Hydrogen peroxide
Dipyridyl
Mutagenesis
Iron
Fenton reaction
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001100003

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001100003

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