The Matrikine Acetylated Proline-Glycine-Proline Couples Vascular Inflammation and Acute Cardiac Rejection

The Matrikine Acetylated Proline-Glycine-Proline Couples Vascular Inflammation and Acute Cardiac Rejection

Abstract The extracellular matrix (ECM) is a dynamic, bioactive structure critical to organ development, structure and function. Excessive remodeling of the ECM is a hallmark of a variety of inflammatory conditions including vascular disease. Endothelin-1 (ET1) synthesis is understood to promote car...

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Bibliographic Details
Main Authors: Gregory A. Payne, Jindong Li, Xin Xu, Patricia Jackson, Hongwei Qin, David M. Pollock, J. Michael Wells, Suzanne Oparil, Massoud Leesar, Rakesh P. Patel, J. Edwin Blalock, Amit Gaggar
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07610-0

Internet

https://doi.org/10.1038/s41598-017-07610-0

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