A novel lncRNA-miRNA-mRNA triple network identifies lncRNA TWF1 as an important regulator of miRNA and gene expression in coronary artery disease

A novel lncRNA-miRNA-mRNA triple network identifies lncRNA TWF1 as an important regulator of miRNA and gene expression in coronary artery disease

Abstract Background Long non-coding RNAs (lncRNAs) are involved in numerous physiological functions. Yet, their mechanisms in coronary artery disease (CAD) are not well understood. Methods The expression profile of genes associated to CAD was reannotated into the lncRNA-mRNA biphasic profile. The ta...

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Bibliographic Details
Main Authors: Liu Miao, Rui-Xing Yin, Qing-Hui Zhang, Xi-Jiang Hu, Feng Huang, Wu-Xian Chen, Xiao-Li Cao, Jin-Zhen Wu
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Nutrition & Metabolism
Subjects:
Coronary artery disease
LncRNA-miRNA-mRNA regulators
Triple network analyses
Function enrichment
Biomarker of diagnosis
Online Access:http://link.springer.com/article/10.1186/s12986-019-0366-3

Internet

http://link.springer.com/article/10.1186/s12986-019-0366-3

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