Transcriptome-wide prediction of miRNA targets in human and mouse using FASTH.

Transcriptome-wide prediction of miRNA targets in human and mouse using FASTH.

Transcriptional regulation by microRNAs (miRNAs) involves complementary base-pairing at target sites on mRNAs, yielding complex secondary structures. Here we introduce an efficient computational approach and software (FASTH) for genome-scale prediction of miRNA target sites based on minimizing the f...

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Bibliographic Details
Main Authors: Chikako Ragan, Nicole Cloonan, Sean M Grimmond, Michael Zuker, Mark A Ragan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2684643?pdf=render

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http://europepmc.org/articles/PMC2684643?pdf=render

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