Antiviral Properties of ISG15

The type I interferon system plays a critical role in limiting the spread of viral infection. Viruses induce the production of interferon (IFN), which after binding to the IFN-α/β receptor (IFNAR), and triggering of the JAK/STAT signaling cascade, results in the induction of interferon-stimulated ge...

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Bibliographic Details
Main Author: Deborah J. Lenschow
Format: Article
Language:English
Published: MDPI AG 2010-09-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/2/10/2154/