Development of a HLA-B*58:01 Allele Screening System for Allopurinol-Induced Severe Cutaneous Adverse Reactions Detection
The HLA-B*58:01 allele has been identified as a genetic marker in the fatal allopurinol-induced severe cutaneous adverse reactions (SCARs) such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). However, the screening of the HLA-B*58:01 allele prior to allopurinol prescription h...
Main Authors: | Kok Beng Gan, Kim Soon Chong, Anusha Devi Nawoor, Sue-Mian Then, Nor Azian Abdul Murad, A. Rahman A. Jamal |
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Format: | Article |
Language: | English |
Published: |
IEEE
2020-01-01
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Series: | IEEE Access |
Subjects: | |
Online Access: | https://ieeexplore.ieee.org/document/9293282/ |
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