A Developmental Perspective on Paragangliar Tumorigenesis

A Developmental Perspective on Paragangliar Tumorigenesis

In this review, we propose that paraganglioma is a fundamentally organized, albeit aberrant, tissue composed of neoplastic vascular and neural cell types that share a common origin from a multipotent mesenchymal-like stem/progenitor cell. This view is consistent with the pseudohypoxic footprint impl...

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Bibliographic Details
Main Authors: Lavinia Vittoria Lotti, Simone Vespa, Mattia Russel Pantalone, Silvia Perconti, Diana Liberata Esposito, Rosa Visone, Angelo Veronese, Carlo Terenzio Paties, Mario Sanna, Fabio Verginelli, Cecilia Soderberg Nauclér, Renato Mariani-Costantini
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cancers
Subjects:
carotid body
angiogenesis
mitochondria
neural crest
neurogenesis
paraganglioma
stem-like tumor cells
vasculogenesis
xenograft
Online Access:https://www.mdpi.com/2072-6694/11/3/273

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https://www.mdpi.com/2072-6694/11/3/273

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