Fish oil ingestion reduces the number of aberrant crypt foci and adenoma in 1,2-dimethylhydrazine-induced colon cancer in rats

Fish oil ingestion reduces the number of aberrant crypt foci and adenoma in 1,2-dimethylhydrazine-induced colon cancer in rats

We determined the effect of fish oil (FO) ingestion on colonic carcinogenesis in rats. Male Wistar rats received 4 subcutaneous injections (40 mg/kg body weight each) of 1,2-dimethylhydrazine (DMH) at 3-day intervals and were fed a diet containing 18% by weight FO (N = 10) or soybean oil (SO, N = 10...

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Bibliographic Details
Main Authors: A.P.B. Moreira, C.M. Sabarense, C.M.G.C. Dias, W. Lunz, A.J. Natali, M.B.A. Glória, M.C.G. Peluzio
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2009-12-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Colonic aberrant crypt foci
Colorectal cancer prevention
Colorectal tumor
Omega-3 fatty acids
Polyamines
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001200008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001200008

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