ProGeo-neo: a customized proteogenomic workflow for neoantigen prediction and selection

ProGeo-neo: a customized proteogenomic workflow for neoantigen prediction and selection

Abstract Background Neoantigens can be differentially recognized by T cell receptor (TCR) as these sequences are derived from mutant proteins and are unique to the tumor. The discovery of neoantigens is the first key step for tumor-specific antigen (TSA) based immunotherapy. Based on high-throughput...

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Bibliographic Details
Main Authors: Yuyu Li, Guangzhi Wang, Xiaoxiu Tan, Jian Ouyang, Menghuan Zhang, Xiaofeng Song, Qi Liu, Qibin Leng, Lanming Chen, Lu Xie
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Medical Genomics
Subjects:
Neoantigen prediction
Proteogenomics
Workflow
Immunogenicity screening
Online Access:http://link.springer.com/article/10.1186/s12920-020-0683-4

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http://link.springer.com/article/10.1186/s12920-020-0683-4

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