Early treatment with combination of SS31 and entresto effectively preserved the heart function in doxorubicin-induced dilated cardiomyopathic rat

Early treatment with combination of SS31 and entresto effectively preserved the heart function in doxorubicin-induced dilated cardiomyopathic rat

Background: This study tested the hypothesis that early administration of SS31 and entresto (En) was superior to either one alone on preserving the heart function in setting of dilated cardiomyopathy (DCM) induced by doxorubicin (Dox) [accumulated dosage of 12.5 mg/kg/administered by intraperitoneal...

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Bibliographic Details
Main Authors: Jui-Ning Yeh, Pei-Hsun Sung, John Y. Chiang, Jiunn-Jye Sheu, Chi-Ruei Huang, Yi-Ching Chu, Sarah Chua, Hon-Kan Yip
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Dilated cardiomyopathy
SS31
Doxorubicin
Entresto
Inflammation
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221006685

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http://www.sciencedirect.com/science/article/pii/S0753332221006685

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