Topographic correlates of driver mutations and endogenous gene expression in pediatric diffuse midline gliomas and hemispheric high-grade gliomas

Abstract We evaluate the topographic distribution of diffuse midline gliomas and hemispheric high-grade gliomas in children with respect to their normal gene expression patterns and pathologic driver mutation patterns. We identified 19 pediatric patients with diffuse midline or high-grade glioma wit...

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Bibliographic Details
Main Authors: Eve Kazarian, Asher Marks, Jin Cui, Armine Darbinyan, Elizabeth Tong, Sabine Mueller, Soonmee Cha, Mariam S. Aboian
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92943-0