Helium Protects Against Lipopolysaccharide-Induced Cardiac Dysfunction in Mice via Suppressing Toll-Like Receptor 4-Nuclear Factor κB-Tumor Necrosis Factor-Alpha/ Interleukin-18 Signaling

Helium Protects Against Lipopolysaccharide-Induced Cardiac Dysfunction in Mice via Suppressing Toll-Like Receptor 4-Nuclear Factor κB-Tumor Necrosis Factor-Alpha/ Interleukin-18 Signaling

The nonanesthetic noble gas helium (He) can protect many organs against ischemia and reperfusion injury, such as liver and heart. However, the role of He on cardiac dysfunction during sepsis is not clear. In this study, we established a lipopolysaccharide (LPS)-induced cardiac dysfunction mouse mode...

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Bibliographic Details
Main Authors: Yaxing Zhang, Jiongshan Zhang, Kangquan Xu, Zifeng Chen, Xiaodan Xu, Jingting Xu, Shuhui Zheng, Min Dai, Hongzhi Yang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Chinese Journal of Physiology
Subjects:
helium
interleukin-18
lipopolysaccharide
nuclear factor-κb
septic cardiomyopathy
toll-like receptor 4
tumor necrosis factor-alpha
Online Access:http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2020;volume=63;issue=6;spage=276;epage=285;aulast=Zhang

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http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2020;volume=63;issue=6;spage=276;epage=285;aulast=Zhang

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