The genealogical population dynamics of HIV-1 in a large transmission chain: bridging within and among host evolutionary rates.

Transmission lies at the interface of human immunodeficiency virus type 1 (HIV-1) evolution within and among hosts and separates distinct selective pressures that impose differences in both the mode of diversification and the tempo of evolution. In the absence of comprehensive direct comparative ana...

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Main Authors: Bram Vrancken, Andrew Rambaut, Marc A Suchard, Alexei Drummond, Guy Baele, Inge Derdelinckx, Eric Van Wijngaerden, Anne-Mieke Vandamme, Kristel Van Laethem, Philippe Lemey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24699231/pdf/?tool=EBI