Curative effect of xanthohumol supplementation during liver fluke-associated cholangiocarcinogenesis: Potential involvement of autophagy

Curative effect of xanthohumol supplementation during liver fluke-associated cholangiocarcinogenesis: Potential involvement of autophagy

Xanthohumol (XH), a plant flavonoid, was shown to attenuate cholangiocarcinoma (CCA) development induced by the liver fluke Opisthorchis viverrini (Ov) and N-dinitrosomethylamine (NDMA) in the hamster model. We investigated the possible involvement of autophagy, a self-degrading process dysregulated...

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Bibliographic Details
Main Authors: Suyanee Thongchot, Malinee Thanee, Watcharin Loilome, Anchalee Techasen, Thidarat Boonmars, Prakasit Sa-Ngiamwibool, Attapol Titapun, Puangrat Yongvanit, Ciro Isidoro, Nisana Namwat
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Journal of Traditional and Complementary Medicine
Subjects:
Apoptosis
BECLIN1
Cancer
Cholangiocarcinoma
Herbal medicine
Flavonoids
Online Access:http://www.sciencedirect.com/science/article/pii/S2225411018308599

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http://www.sciencedirect.com/science/article/pii/S2225411018308599

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