Draft crystal structure of the vault shell at 9-A resolution.

Vaults are the largest known cytoplasmic ribonucleoprotein structures and may function in innate immunity. The vault shell self-assembles from 96 copies of major vault protein and encapsulates two other proteins and a small RNA. We crystallized rat liver vaults and several recombinant vaults, all am...

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Bibliographic Details
Main Authors: Daniel H Anderson, Valerie A Kickhoefer, Stuart A Sievers, Leonard H Rome, David Eisenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2229873?pdf=render