RARG Gene Dysregulation in Acute Myeloid Leukemia

Retinoic acid receptor γ (RARγ) belongs to the nuclear receptor superfamily and shares 90% homology with retinoic acid receptor α (RARα) and retinoic acid receptor β (RARβ). RARA rearrangements are well-known to be involved in acute promyelocytic leukemia (APL), but RARG rearrangements can also rese...

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Bibliographic Details
Main Authors: Maria Rosa Conserva, Immacolata Redavid, Luisa Anelli, Antonella Zagaria, Giorgina Specchia, Francesco Albano
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Molecular Biosciences
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Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2019.00114/full