Different temperature thresholds for antipyretic intervention in critically ill children with fever due to infection: the FEVER feasibility RCT

Different temperature thresholds for antipyretic intervention in critically ill children with fever due to infection: the FEVER feasibility RCT

Background: Fever accelerates host immune system control of pathogens but at a high metabolic cost. The optimal approach to fever management and the optimal temperature thresholds used for treatment in critically ill children are unknown. Objectives: To determine the feasibility of conducting a defi...

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Main Authors: Mark J Peters, Imran Khan, Kerry Woolfall, Elizabeth Deja, Paul R Mouncey, Jerome Wulff, Alexina Mason, Rachel Agbeko, Elizabeth S Draper, Blaise Fenn, Doug W Gould, Abby Koelewyn, Nigel Klein, Christine Mackerness, Sian Martin, Lauran O’Neill, Padmanabhan Ramnarayan, Shane Tibby, Lyvonne Tume, Jason Watkins, Kent Thorburn, Paul Wellman, David A Harrison, Kathryn M Rowan
Format: Article
Language:English
Published: NIHR Journals Library 2019-02-01
Series:Health Technology Assessment
Online Access:https://doi.org/10.3310/hta23050

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