Optimal age for genetic cancer predisposition testing in hereditary SMARCA4 Ovarian Cancer Families: How young is too young?

Small cell carcinoma of the ovary, hypercalcemic type is a rare, aggressive, and typically fatal ovarian cancer that primarily affects young women less than 40 years of age. It is caused by a pathogenic variant in the SMARCA4 gene, with nearly half of patients found to have germline pathogenic varia...

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Bibliographic Details
Main Authors: Sarah E. Podwika, Taylor M. Jenkins, Joyti K. Khokhar, Sarah H. Erickson, Susan C. Modesitt
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Gynecologic Oncology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578920300357