Predicting Blood Concentration of Tacrolimus in Patients With Autoimmune Diseases Using Machine Learning Techniques Based on Real-World Evidence

Predicting Blood Concentration of Tacrolimus in Patients With Autoimmune Diseases Using Machine Learning Techniques Based on Real-World Evidence

Tacrolimus is a widely used immunosuppressive drug in patients with autoimmune diseases. It has a narrow therapeutic window, thus requiring therapeutic drug monitoring (TDM) to guide the clinical regimen. This study included 193 cases of tacrolimus TDM data in patients with autoimmune diseases at So...

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Bibliographic Details
Main Authors: Ping Zheng, Ze Yu, Liren Li, Shiting Liu, Yan Lou, Xin Hao, Peng Yu, Ming Lei, Qiaona Qi, Zeyuan Wang, Fei Gao, Yuqing Zhang, Yilei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
blood concentration prediction
therapeutic drug monitoring
machine learning
tacrolimus
autoimmune disease
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.727245/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.727245/full

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