Development of a Porcine Full-Thickness Burn Hypertrophic Scar Model and Investigation of the Effects of Shikonin on Hypertrophic Scar Remediation

Hypertrophic scars formed after burns remain a challenge in clinical practice. Development of effective scar therapies relies on validated animal models that mimic human hypertrophic scars. A consistent porcine full-thickness burn hypertrophic scar model has yet to be developed. We have previously r...

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Bibliographic Details
Main Authors: Xingwang Deng, Qian Chen, Lijuan Qiang, Mingwei Chi, Nan Xie, Yinsheng Wu, Ming Yao, Dan Zhao, Jiaxiang Ma, Ning Zhang, Yan Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00590/full