Telomere recombination accelerates cellular aging in Saccharomyces cerevisiae.
Telomeres are nucleoprotein structures located at the linear ends of eukaryotic chromosomes. Telomere integrity is required for cell proliferation and survival. Although the vast majority of eukaryotic species use telomerase as a primary means for telomere maintenance, a few species can use recombin...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-06-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2694356?pdf=render |