Telomere recombination accelerates cellular aging in Saccharomyces cerevisiae.

Telomeres are nucleoprotein structures located at the linear ends of eukaryotic chromosomes. Telomere integrity is required for cell proliferation and survival. Although the vast majority of eukaryotic species use telomerase as a primary means for telomere maintenance, a few species can use recombin...

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Bibliographic Details
Main Authors: Xiao-Fen Chen, Fei-Long Meng, Jin-Qiu Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2694356?pdf=render