Potential role for HIV-specific CD38-/HLA-DR+ CD8+ T cells in viral suppression and cytotoxicity in HIV controllers.

Potential role for HIV-specific CD38-/HLA-DR+ CD8+ T cells in viral suppression and cytotoxicity in HIV controllers.

BACKGROUND:HIV controllers (HIC) are rare HIV-1-infected patients who exhibit spontaneous viral control. HIC have high frequency of CD38-/HLA-DR+ HIV-specific CD8+ T cells. Here we examined the role of this subset in HIC status. MATERIALS AND METHODS:We compared CD38-/HLA-DR+ CD8+ T cells with the c...

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Bibliographic Details
Main Authors: Stéphane Hua, Camille Lécuroux, Asier Sáez-Cirión, Gianfranco Pancino, Isabelle Girault, Pierre Versmisse, Faroudy Boufassa, Olivier Taulera, Martine Sinet, Olivier Lambotte, Alain Venet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4084978?pdf=render

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http://europepmc.org/articles/PMC4084978?pdf=render

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