Direct Oral Anticoagulants Form Thrombus Different From Warfarin in a Microchip Flow Chamber System

Abstract Direct oral anticoagulants (DOACs) have low risk of intracranial hemorrhage compared to warfarin. We sought to clarify the different mechanisms responsible for suppression of bleeding events using the Total Thrombus-formation Analysis System (T-TAS), a flow-microchip chamber with thrombogen...

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Bibliographic Details
Main Authors: Masanobu Ishii, Koichi Kaikita, Miwa Ito, Daisuke Sueta, Yuichiro Arima, Seiji Takashio, Yasuhiro Izumiya, Eiichiro Yamamoto, Megumi Yamamuro, Sunao Kojima, Seiji Hokimoto, Hiroshige Yamabe, Hisao Ogawa, Kenichi Tsujita
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07939-6