Alterations of the Immunologic Co-Stimulator B7 and TNFR Families Correlate with Hepatocellular Carcinoma Prognosis and Metastasis by Inactivating STAT3

Alterations of the Immunologic Co-Stimulator B7 and TNFR Families Correlate with Hepatocellular Carcinoma Prognosis and Metastasis by Inactivating STAT3

Blockade of the immunosuppressive checkpoint receptors cytotoxic T-lymphocyte-associated protein 4 (CTLA4) or programmed death 1 (PD-1) and its cognate ligand, programmed death 1 ligand (PD-L1), has altered the landscape of anti-tumor immunotherapy. B7 family and tumor necrosis factor receptor (TNFR...

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Bibliographic Details
Main Authors: Yi-Ming Li, Zhen-Yu Liu, Zhu-Chun Li, Jian-Chao Wang, Jing-Min Yu, Hai-Jiao Yang, Zhi-Nan Chen, Juan Tang
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
immune landscape
liver cancer
metastasis
Online Access:http://www.mdpi.com/1422-0067/20/1/156

Internet

http://www.mdpi.com/1422-0067/20/1/156

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