Staphylococcus aureus adhesion in endovascular infections is controlled by the ArlRS-MgrA signaling cascade.

Staphylococcus aureus is a leading cause of endovascular infections. This bacterial pathogen uses a diverse array of surface adhesins to clump in blood and adhere to vessel walls, leading to endothelial damage, development of intravascular vegetations and secondary infectious foci, and overall disea...

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Bibliographic Details
Main Authors: Jakub M Kwiecinski, Heidi A Crosby, Claire Valotteau, Joseph A Hippensteel, Manasa K Nayak, Anil K Chauhan, Eric P Schmidt, Yves F Dufrêne, Alexander R Horswill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007800