Recreating Tumour Complexity in a Dish: Organoid Models to Study Liver Cancer Cells and their Extracellular Environment

Recreating Tumour Complexity in a Dish: Organoid Models to Study Liver Cancer Cells and their Extracellular Environment

Primary liver cancer, consisting predominantly of hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), remains one of the most lethal malignancies worldwide. This high malignancy is related to the complex and dynamic interactions between tumour cells, stromal cells and the extracellular envi...

Full description

Bibliographic Details
Main Authors: Gilles S. van Tienderen, Bas Groot Koerkamp, Jan N.M. IJzermans, Luc J.W. van der Laan, Monique M.A. Verstegen
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cancers
Subjects:
tumour organoids
primary liver cancer
extracellular matrix
disease modelling
Online Access:https://www.mdpi.com/2072-6694/11/11/1706

Internet

https://www.mdpi.com/2072-6694/11/11/1706

Similar Items