The GC Skew Index: A Measure of Genomic Compositional Asymmetry and the Degree of Replicational Selection

The GC Skew Index: A Measure of Genomic Compositional Asymmetry and the Degree of Replicational Selection

Circular bacterial chromosomes have highly polarized nucleotide composition in the two replichores, and this genomic strand asymmetry can be visualized using GC skew graphs. Here we propose and discuss the GC skew index (GCSI) for the quantification of genomic compositional skew, which combines a no...

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Bibliographic Details
Main Authors: Masaru Tomita, Kazuharu Arakawa
Format: Article
Language:English
Published: SAGE Publishing 2007-01-01
Series:Evolutionary Bioinformatics
Subjects:
GC skew
DNA replication
replicational selection
fast Fourier transforms
bioinformatics
GCSI
Online Access:http://la-press.com/article.php?article_id=349

Internet

http://la-press.com/article.php?article_id=349

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