LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells

LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells

Regulation of gene expression of ATP-binding cassette transporter (ABC)A1 and ABCG1 by liver X receptor/retinoid X receptor (LXR/RXR) ligands was investigated in the human intestinal cell line CaCo-2. Neither the RXR ligand, 9-cis retinoic acid, nor the natural LXR ligand 22-hydroxycholesterol alone...

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Bibliographic Details
Main Authors: Shubha Murthy, Ella Born, Satya N. Mathur, F. Jeffrey Field
Format: Article
Language:English
Published: Elsevier 2002-07-01
Series:Journal of Lipid Research
Subjects:
liver X receptor
retinoid X receptor
9-cis retinoic acid
22-hydroxycholesterol
T0901317
ABCA1
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752031467X

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http://www.sciencedirect.com/science/article/pii/S002222752031467X

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