Vitamin E deficiency dysregulates thiols, amino acids and related molecules during zebrafish embryogenesis

Vitamin E (α-tocopherol, VitE) was discovered as a nutrient essential to protect fetuses, but its molecular role in embryogenesis remains undefined. We hypothesize that the increased lipid peroxidation due to VitE deficiency drives a complex mechanism of overlapping biochemical pathways needed to ma...

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Bibliographic Details
Main Authors: Jie Zhang, Brian Head, Scott W. Leonard, Jaewoo Choi, Robyn L. Tanguay, Maret G. Traber
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720309897