Upregulation of liver VLDL receptor and FAT/CD36 expression in LDLR−/− apoB100/100 mice fed trans-10,cis-12 conjugated linoleic acid1

This study explores the mechanisms responsible for the fatty liver setup in mice fed trans-10,cis-12 conjugated linoleic acid (t10c12 CLA), hypothesizing that an induction of low density lipoprotein receptor (LDLR) expression is associated with lipid accumulation. To this end, the effects of t10c12...

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Bibliographic Details
Main Authors: Pascal Degrace, Bastien Moindrot, Ismaël Mohamed, Joseph Gresti, Zhen-Yu Du, Jean-Michel Chardigny, Jean-Louis Sébédio, Pierre Clouet
Format: Article
Language:English
Published: Elsevier 2006-12-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520432572