Autoantibodies against the Second Extracellular Loop of M3R Do neither Induce nor Indicate Primary Sjögren's Syndrome.

OBJECTIVES:Anti-muscarinic acetylcholine type-3 receptor (anti-M3R) autoantibodies have been suggested to be pathogenic for primary Sjögren's syndrome (pSS), and the second extracellular loop of M3R is suspected to carry a disease-promoting epitope. In this study, we aimed to evaluate the patho...

Full description

Bibliographic Details
Main Authors: Yan Chen, Junfeng Zheng, Qiaoniang Huang, Fengyuan Deng, Renliang Huang, Wenjie Zhao, Junping Yin, Lina Song, Juan Chen, Xing Gao, Zuguo Liu, Frank Petersen, Xinhua Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4765836?pdf=render