Unmethylated CpG motif-containing genomic DNA fragment of promotes macrophage functions through TLR9-mediated activation of NF-B and MAPKs signaling pathways
The potency of synthetic CpG-oligo-deoxynucleotides (CpG-ODNs) adjuvants in modulating the immune cell functions through the TLR pathway has been tested and reported previously. However, the cellular signaling involved in the stimulation of macrophages by natural, CpG motif-containing adjuvant and t...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2020-04-01
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| Series: | Innate Immunity |
| Online Access: | https://doi.org/10.1177/1753425919879997 |