Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD–scid IL-2rgnull RIP-DTR mice engrafted with human islets

Chaoxing Yang,1 Matthias Loehn,2 Agata Jurczyk,1 Natalia Przewozniak,1 Linda Leehy,1 Pedro L Herrera,3 Leonard D Shultz,4 Dale L Greiner,1 David M Harlan,5 Rita Bortell1 1Program in Molecular Medicine, Diabetes Center of Excellence, University of Massachusetts Medical School, Worcester, MA, USA; 2Sa...

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Bibliographic Details
Main Authors: Yang C, Loehn M, Jurczyk A, Przewozniak N, Leehy L, Herrera PL, Shultz LD, Greiner DL, Harlan DM, Bortell R
Format: Article
Language:English
Published: Dove Medical Press 2015-08-01
Series:Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy
Online Access:http://www.dovepress.com/lixisenatide-accelerates-restoration-of-normoglycemia-and-improves-hum-peer-reviewed-article-DMSO