Protective Effects of Agmatine against Chlorpromazine- Induced Toxicity in the Liver of Wistar Rats

Protective Effects of Agmatine against Chlorpromazine- Induced Toxicity in the Liver of Wistar Rats

The metabolic pathways of chlorpromazine (CPZ) toxicity were tracked by assessing oxidative/nitrosative stress markers. The main objective of the study was to test the hypothesis that agmatine (AGM) prevents oxidative/nitrosative stress in the liver of Wistar rats 15 days after administration of CPZ...

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Bibliographic Details
Main Authors: Dejanović Bratislav, Stevanović Ivana, Ninković Milica, Stojanović Ivana, Lavrnja Irena, Radičević Tatjana
Format: Article
Language:English
Published: Sciendo 2016-03-01
Series:Acta Facultatis Medicae Naissensis
Subjects:
agmatine
antioxidant defense
chlorpromazine
liver
oxidative stress
Online Access:http://www.degruyter.com/view/j/afmnai.2016.33.issue-1/afmnai-2016-0002/afmnai-2016-0002.xml?format=INT

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http://www.degruyter.com/view/j/afmnai.2016.33.issue-1/afmnai-2016-0002/afmnai-2016-0002.xml?format=INT

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