Increased ghrelin but low ghrelin-reactive immunoglobulins in a rat model of methotrexate chemotherapy-induced anorexia

Increased ghrelin but low ghrelin-reactive immunoglobulins in a rat model of methotrexate chemotherapy-induced anorexia

Background and aims: Cancer chemotherapy is commonly accompanied by mucositis, anorexia, weight loss and anxiety independently from cancer-induced anorexia-cachexia, further aggravating clinical outcome. Ghrelin is a peptide hormone produced in gastric mucosa that reaches the brain to stimulate appe...

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Bibliographic Details
Main Authors: Marie François, Kuniko Takagi, Romain Legrand, Nicolas Lucas, Stephanie Beutheu Youmba, Christine Bôle-Feysot, Aurore Cravezic, Naouel Tennoune, Jean-Claude do Rego, Moïse Coëffier, Akio Inui, Pierre Déchelotte, Sergueï O. Fetissov
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Nutrition
Subjects:
Anorexia
Autoantibodies
Ghrelin
chemotherapy
intestinal inflammation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnut.2016.00023/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnut.2016.00023/full

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