Pangenome Analysis of Burkholderia pseudomallei: Genome Evolution Preserves Gene Order despite High Recombination Rates.

The pangenomic diversity in Burkholderia pseudomallei is high, with approximately 5.8% of the genome consisting of genomic islands. Genomic islands are known hotspots for recombination driven primarily by site-specific recombination associated with tRNAs. However, recombination rates in other portio...

Full description

Bibliographic Details
Main Authors: Senanu M Spring-Pearson, Joshua K Stone, Adina Doyle, Christopher J Allender, Richard T Okinaka, Mark Mayo, Stacey M Broomall, Jessica M Hill, Mark A Karavis, Kyle S Hubbard, Joseph M Insalaco, Lauren A McNew, C Nicole Rosenzweig, Henry S Gibbons, Bart J Currie, David M Wagner, Paul Keim, Apichai Tuanyok
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4613141?pdf=render