The role of fatty acid metabolism and lipotoxicity in pancreatic β-cell injury: Identification of potential therapeutic targets

Over the last 20 years, intensive research has been focused on the specific mechanisms mediating the pancreatic β-cell injury. Both the decreased viability and the dysfunction of β-cells have become the key factors in the development of diabetes mellitus. Thus, it is of utmost importance to elucidat...

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Bibliographic Details
Main Authors: Haopeng Yang, Xuejun Li
Format: Article
Language:English
Published: Elsevier 2012-08-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383512000834