Functional copy-number alterations in cancer.

Functional copy-number alterations in cancer.

Understanding the molecular basis of cancer requires characterization of its genetic defects. DNA microarray technologies can provide detailed raw data about chromosomal aberrations in tumor samples. Computational analysis is needed (1) to deduce from raw array data actual amplification or deletion...

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Bibliographic Details
Main Authors: Barry S Taylor, Jordi Barretina, Nicholas D Socci, Penelope Decarolis, Marc Ladanyi, Matthew Meyerson, Samuel Singer, Chris Sander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2527508?pdf=render

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http://europepmc.org/articles/PMC2527508?pdf=render

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