Solution structures of the acyl carrier protein domain from the highly reducing type I iterative polyketide synthase CalE8.

Solution structures of the acyl carrier protein domain from the highly reducing type I iterative polyketide synthase CalE8.

Biosynthesis of the enediyne natural product calicheamicins γ(1) (I) in Micromonospora echinospora ssp. calichensis is initiated by the iterative polyketide synthase (PKS) CalE8. Recent studies showed that CalE8 produces highly conjugated polyenes as potential biosynthetic intermediates and thus bel...

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Bibliographic Details
Main Authors: Jackwee Lim, Rong Kong, Elavazhagan Murugan, Chun Loong Ho, Zhao-Xun Liang, Daiwen Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3107222?pdf=render

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http://europepmc.org/articles/PMC3107222?pdf=render

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