Automatic Prediction of Protein 3D Structures by Probabilistic Multi-template Homology Modeling.

Homology modeling predicts the 3D structure of a query protein based on the sequence alignment with one or more template proteins of known structure. Its great importance for biological research is owed to its speed, simplicity, reliability and wide applicability, covering more than half of the resi...

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Bibliographic Details
Main Authors: Armin Meier, Johannes Söding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4619893?pdf=render